Hand of Vecna + Medomai the Ageless Combos

1 known combo featuring both cards in Commander

Infinite turns Lock

Combo 1 with The Book of Vile Darkness + Eye of Vecna + True Polymorph

Also requires: The Book of Vile Darkness The Book of Vile Darkness Eye of Vecna Eye of Vecna True Polymorph True Polymorph
Results: Infinite turns · Lock
Steps
  1. On the end step prior to your turn, cast True Polymorph by paying {4}{U}{U}, causing Medomai to become a copy of Eye of Vecna.
  2. Activate The Book of Vile Darkness by tapping it and exiling it, Medomai and Hand of Vecna, causing you to create a legendary 8/8 Vecna token that has all triggered abilities of the exiled cards.
  3. During your next turn, deal combat damage to an opponent using Vecna.
  4. Vecna triggers, causing you to take an extra turn after this one.
  5. Repeat from step 3 during each of your turns.
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